Name: Sickle Cell Genetics Lab: Diagnosing Baby Marie™
SKU: KT-1502-01
Availability: InStock

Sickle Cell Genetics Lab: Diagnosing Baby Marie™ - Image 1

Sickle Cell Genetics Lab: Diagnosing Baby Marie™

$69.00

ALL NEW CURRICULUM! Will baby Marie be affected by sickle cell disease? Use gel electrophoresis to analyze her family’s DNA for the sickle cell allele.

SKU: KT-1502-01 Categories: Biomedical Science Learning Labs, DNA gel electrophoresis, Learning Labs™

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Sickle Cell Genetics Lab: Diagnosing Baby Marie™

Learning Lab Companion Kit

Add microtubes and gel electrophoresis consumables for blueGel™ or Bandit™

$36.00

Optional Learning Lab Companion Kit includes: 50 microtubes, 100 PCR tubes, 30 ml 20X TBE buffer, 8 GelGreen® Agarose Tabs™

Description

New Curriculum! In this engaging case study, students test a fictional family for sickle cell disease. The Patel family has two children, one of whom has had an initial test result indicating possible sickle cell disease. Students will use gel electrophoresis to test the Patel family for the sickle cell allele and give baby Marie a definitive diagnosis.

Techniques: Micropipetting, gel electrophoresis
Topics: Genotype to phenotype, inheritance, genetic disease
Level: General high school, advanced high school, college
Time required: One 45-minute class period

What’s included

DNA samples for eight lab groups:

4 Simulated patient DNA samples
Fast DNA Ladder 1

Storage notes:

If kept in the freezer, reagents can be stored for 12 months after receipt.
If kept in the refrigerator, reagents can be stored for 6 months after receipt.

Requirements

Required equipment:

2-20 μl variable volume or 10 μl fixed volume micropipettes and tips
Gel electrophoresis and fluorescence visualization system (e.g. blueGel electrophoresis system)

Gel electrophoresis reagents and plastic tubes are supplied by the user

Agarose
Gel electrophoresis buffer (e.g. TBE)
Fluorescent DNA stain (e.g. SeeGreen™ or GelGreen®)
Plastic tubes for distributing samples to student groups

The Learning Lab Companion Kit (KT-1510-01) provides sufficient reagents to prepare and run eight gels when using the blueGel electrophoresis system, as well as plastic tubes to distribute samples to student groups.